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Antiproliferative and structure activity relationships of amaryllidaceae alkaloids

dc.contributor.authorCedrón, Juan C.
dc.contributor.authorRavelo, Ángel G.
dc.contributor.authorLeón, Leticia G.
dc.contributor.authorPadrón, José M.
dc.contributor.authorEstévez-Braun, Ana
dc.date.accessioned2021-03-17T18:06:34Z
dc.date.available2021-03-17T18:06:34Z
dc.date.issued2015-07-30
dc.identifier.issn1420-3049es_PE
dc.identifier.urihttps://hdl.handle.net/20.500.12815/215
dc.description.abstractThe antiproliferative activity of a set of seven natural Amaryllidaceae alkaloids and 32 derivatives against four cancer cell lines (A2780, SW1573, T47-D and WiDr) was determined. The best antiproliferative activities were achieved with alkaloids derived from pancracine (2), haemanthamine (6) and haemantidine (7). For each skeleton, some structure-activity relationships were outlined.es_PE
dc.formatapplication/pdfes_PE
dc.language.isoenges_PE
dc.publisherMDPIes_PE
dc.rightsinfo:eu-repo/semantics/openAccesses_PE
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.sourceRepositorio Institucional UTECes_PE
dc.sourceUniversidad de Ingeniería y Tecnología - UTECes_PE
dc.subjectAmarylidaceae alkaloidses_PE
dc.subjectAntiproliferative activityes_PE
dc.subjectSARes_PE
dc.titleAntiproliferative and structure activity relationships of amaryllidaceae alkaloidses_PE
dc.typeinfo:eu-repo/semantics/articlees_PE
dc.identifier.doihttps://doi.org/10.3390/molecules200813854es_PE
dc.identifier.journalMoleculeses_PE


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